Therapeutic
Areas
 

Resources

Links

http://www.hsc.unt.edu/education/pace/online.cfm

http://www.ceconcepts.net/

http://www.impactedu.net/activities.htm

http://www.axdevgroup.com/index.php?language=en

http://www.mededarchitects.com/

http://thecmelounge.com/2/

http://www.mycme.com/

http://www.mdlinx.com/

Presentation Slides

Presentation Slides for Dr. William Gradishar: Breast Cancer Heterogeneity: Providing the Need and the Rationale for Molecular Profiling.

Presentation Slides for Dr. D. Craig Allred: Use of Multi-gene Molecular Profiling to Exploit Molecular Heterogeneity.

Presentation Slides for Dr. Terry Mamounas: Commercially Available Multi-gene Assays: Moving Toward Personalized Medicine in Breast Cancer.

References

Practice Recommendations

  1. ASCO guidelines: Harris L, Fritsche H, Mennel R, et al; American Society of Clinical Oncology. Practice recommendations discussed during this activity come from the following sources: American Society of Clinical Oncology 2007 update of recommendations for the use of tumor markers in breast cancer. J Clin Oncol. 2007 Nov 20;25(33):5287-312.
  2. NCCN guidelines: NCCN Practice Guidelines in Oncology. Breast cancer. v.1.2010

Publications

  1. Foekens JA, Atkins D, Zhang Y, et al. Multicenter validation of a gene expression-based prognostic signature in lymph node-negative primary breast cancer. J Clin Oncol. 2006 Apr 10;24(11):1665-71.
  2. Ma XJ, Salunga R, Dahiya S, et al. A five-gene molecular grade index and HOXB13:IL17BR are complementary prognostic factors in early stage breast cancer. Clin Cancer Res. 2008 May 1;14(9):2601-8.
  3. Paik S, Shak S, Tang G, et al. A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer. N Engl J Med. 2004 Dec 30;351(27):2817-26.
  4. Perou CM, Sørlie T, Eisen MB, et al. Molecular portraits of human breast tumours. Nature. 2000 Aug 17;406(6797):747-52.
  5. Sorlie T, Tibshirani R, Parker J, et al. Repeated observation of breast tumor subtypes in independent gene expression data sets. Proc Natl Acad Sci U S A. 2003 Jul 8;100(14):8418-23.
  6. van de Vijver MJ, He YD, van't Veer LJ, et al. A gene-expression signature as a predictor of survival in breast cancer. N Engl J Med. 2002 Dec 19;347(25):1999-2009.
  7. van 't Veer LJ, Dai H, van de Vijver MJ, et al. Gene expression profiling predicts clinical outcome of breast cancer. Nature. 2002 Jan 31;415(6871):530-6.